Short answer, no.
Simplifi is designed to always stay in sync with your bank's balance, which allows users the ability to enter missing transactions, delete transactions, or even add transactions further back than what was originally downloaded. Having a running balance column would remove that flexibility.
While we don't offer a balance column, Simplifi does have a projected balance view at the account registers' top. This projected view is designed to show you your future account balance based on the recurring transactions you've created. That way, you can see where you may run into a snag throughout the month!